Slowly progressing amyotrophic lateral sclerosis caused by H46R SOD1 mutation.
نویسندگان
چکیده
Case Report A 55-year-old man of Pakistani descent experienced low back pain and paresis of the left leg without pareses in trunk or arm Dear Sir, We report the first case of familial amyotrophic lateral sclerosis (FALS) caused by H46R SOD1 mutation in a patient of Pakistani descent. H46R SOD1 mutations are associated with a characteristic clinical presentation of slowly progressing paresis of the lower limbs, and the prognosis is much more favorable than in sporadic ALS. The patient presented here Received: December 1, 2006 Accepted: December 21, 2006 Published online: May 4, 2007
منابع مشابه
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ورودعنوان ژورنال:
- European neurology
دوره 58 1 شماره
صفحات -
تاریخ انتشار 2007